Drivers and sensitivities
01 / DRIVERS- Ageing populations and chronic disease growth
- Low physician and hospital capacity per capita
- Expanding insurance coverage
- Local pharmaceutical manufacturing initiatives
- Public health budgets and out-of-pocket spending
- Currency, because drugs and devices are often imported
- Demographic ageing
- Reimbursement and pricing policy
Editorial summary. Qualitative drivers are general industry context written by Invest Global, last reviewed 2026-10-08. They are not forecasts. Figures elsewhere on this page are sourced and dated.
Key risks
02 / RISKS- Price controls and procurement delays
- Payment arrears from public payers
- Counterfeit and quality control issues
- Regulatory approval timelines
- Workforce shortages
Investing in frontier and emerging markets carries significant risk, including total loss. This list is illustrative and not exhaustive.
Value chain
03 / STAGES- Research and manufacturing
- Distribution and supply chain
- Provider networks
- Payers and insurance
- Digital and diagnostic services
Top exposed countries
04 / 193 SCOREDRanked by exposure score, a weighted percentile of sourced indicators. Select Sources on any row to see each input, its period, source and as-of date.
| # | Country | Score | Band | Why |
|---|---|---|---|---|
| 01 | 81 | High | Health spending is 10.7% of GDP; 30.0% of the population is aged 65 or over (2023, 2025). Economy-wide FDI restrictiveness (OECD, 0 open to 1 closed): | |
| 02 | 80 | High | Health spending is 11.5% of GDP; 22.5% of the population is aged 65 or over (2024, 2025). Economy-wide FDI restrictiveness (OECD, 0 open to 1 closed): | |
| 03 | 79 | High | Health spending is 11.3% of GDP; health spending is $6,378 per person (2024). Economy-wide FDI restrictiveness (OECD, 0 open to 1 closed): | |
| 04 | 79 | High | Health spending is 16.7% of GDP; health spending is $13,473 per person (2023). Economy-wide FDI restrictiveness (OECD, 0 open to 1 closed): | |
| 05 | 78 | High | Health spending is 10.5% of GDP; 24.2% of the population is aged 65 or over (2023, 2025). Economy-wide FDI restrictiveness (OECD, 0 open to 1 closed): | |
| 06 | 78 | High | Health spending is 12.3% of GDP; 23.7% of the population is aged 65 or over (2024, 2025). Economy-wide FDI restrictiveness (OECD, 0 open to 1 closed): | |
| 07 | 77 | High | Health spending is 10.8% of GDP; health spending is $5,931 per person (2023). Economy-wide FDI restrictiveness (OECD, 0 open to 1 closed): | |
| 08 | 77 | High | Health spending is 11.1% of GDP; health spending is $5,860 per person (2024). Economy-wide FDI restrictiveness (OECD, 0 open to 1 closed): | |
| 09 | 76 | High | Health spending is 11.7% of GDP; health spending is $11,784 per person (2023). Economy-wide FDI restrictiveness (OECD, 0 open to 1 closed): | |
| 10 | 75 | High | Health spending is 11.8% of GDP; health spending is $6,739 per person (2024). Economy-wide FDI restrictiveness (OECD, 0 open to 1 closed): | |
| 11 | 75 | High | Health spending is $11,495 per person; 21.4% of the population is aged 65 or over (2023, 2025). | |
| 12 | 75 | High | Health spending is 9.9% of GDP; 22.2% of the population is aged 65 or over (2024, 2025). Economy-wide FDI restrictiveness (OECD, 0 open to 1 closed): |
Exposure scores describe how large and relevant a sector is in a country's economy and opportunity set relative to other countries. They are not a measure of attractiveness, expected return or risk. Educational content only, not investment advice.
Largest markets by scale
05 / 189 RANKEDExposure scores show relative weight. This ranking shows absolute size on one sourced measure: health expenditure. World Bank current health expenditure (percent of GDP) times GDP of the same year.
| # | Country | Health expenditure | Period |
|---|---|---|---|
| 01 | 2023 | ||
| 02 | 2023 | ||
| 03 | 2024 | ||
| 04 | 2023 | ||
| 05 | 2024 | ||
| 06 | 2024 | ||
| 07 | 2024 | ||
| 08 | 2023 | ||
| 09 | 2024 | ||
| 10 | 2023 | ||
| 11 | 2024 | ||
| 12 | 2023 |
Derived from the cited sources as described above. A larger economy ranks higher on absolute measures even when the sector is a smaller share of its output.
Top listed companies
06 / PLAYERSLargest listed companies tagged to this sector in the Invest Global capital markets dataset, ranked by market capitalisation in US dollars. Coverage is the markets in that dataset, so it is not a global census.
| # | Company | Country | Market cap | Basis |
|---|---|---|---|---|
| 01 | Roche RO | Invest Global sector tag | ||
| 02 | Novartis NOVN | Invest Global sector tag | ||
| 03 | AstraZeneca AZN | Invest Global sector tag | ||
| 04 | Novo Nordisk NOVO.B | Invest Global sector tag | ||
| 05 | Medtronic MDT | Invest Global sector tag | ||
| 06 | Argenx ARGX | Invest Global sector tag | ||
| 07 | CSL CSL | Invest Global sector tag | ||
| 08 | UCB UCB | Invest Global sector tag | ||
| 09 | Samsung Biologics 207940 | Invest Global sector tag | ||
| 10 | Teva Pharmaceutical Industries TEVA | Invest Global sector tag | ||
| 11 | Novonesis NSIS B | Invest Global sector tag | ||
| 12 | Genmab GMAB | Invest Global sector tag | ||
| 13 | IHH Healthcare IHH | Invest Global sector tag | ||
| 14 | Eurofins Scientific ERF | Invest Global sector tag | ||
| 15 | Fisher & Paykel Healthcare FPH | Invest Global sector tag |
Not recommendations. A list of the largest companies is not a list of suggested investments. Sector tags marked Invest Global are an editorial classification of each company's main business. Market capitalisation is a snapshot, not a live quote.
Regulatory considerations
07 / REGULATION- Drug registration and pricing regimes
- Licensing of facilities and professionals
- Foreign ownership limits on providers
- Import duties on devices and medicines
The OECD FDI Regulatory Restrictiveness Index scores 105 economies from 0 (open) to 1 (closed). The median is , with a range of 0.00 to 0.74. The table above notes the score under each top market where it is covered. Sector-specific restrictions vary and are set out in the OECD regulatory database.
Regulatory summaries are general and change often. Confirm current rules with local counsel. Not legal advice.
Typical entry routes
08 / ACCESS- Listed healthcare and pharmaceutical firms
- Healthcare sector funds
- Private hospital and diagnostic platforms, for qualified investors
- Contract manufacturing and distribution partnerships
- State Street Health Care Select Sector SPDR ETFSELECT SECTOR SPDR TRUST
- Vanguard Health Care Index FundVANGUARD WORLD FUND
- iShares Biotechnology ETFiSHARES TRUST
Examples, not recommendations. Each fund is confirmed in the SEC series and class file. These are US-listed funds whose holdings are mostly developed-market issuers; check each prospectus for current holdings, fees and domicile. No prices, yields or fees are shown because none are verified here.
Sourced charts
09 / DATACharts show historical data from the cited sources. Past levels do not indicate future results. Commodity series are World Bank nominal US dollar monthly benchmarks.
Method and sources
10 / FORMULAEach score is a weighted average of percentile ranks. For every indicator, a country's latest observation (not older than 2014) is ranked against all other countries with data (mid-rank percentile, 0 to 1). Where a lower raw value signals more headroom (for example electricity access), the rank is inverted. The weighted average of the available percentiles is scaled to 0 to 100. A cell is published only if indicators holding at least 60 percent of the weight are available; otherwise the country is omitted for that sector.
| Indicator | Weight | Direction | Source |
|---|---|---|---|
| Current health expenditure | 30% | Scale (higher raw value scores higher) | World Bank, World Development Indicators |
| Population ages 65 and above | 25% | Scale (higher raw value scores higher) | World Bank, World Development Indicators |
| Current health expenditure per capita | 25% | Scale (higher raw value scores higher) | World Bank, World Development Indicators |
| Physicians per 1,000 people | 20% | Headroom (lower raw value scores higher) | World Bank, World Development Indicators |
The score describes how large and relevant a sector is in a country's economy and opportunity set, relative to other countries. It is not a measure of attractiveness, return or risk, and it is not investment advice.
- World Bank, World Development Indicators CC BY 4.0
- U.S. SEC, Investment Company Series and Class Information U.S. Government work, public domain
- companiesmarketcap.com (via the Invest Global capital markets dataset) Third-party data carried over from the existing Invest Global capital markets dataset; reuse licence to be confirmed
- OECD FDI Regulatory Restrictiveness Index CC BY 4.0 (OECD content published from 1 July 2024)
Data version 2026-10-09. Every datapoint carries its source and as-of date; hover or tap a dotted value to see them.